Malignant hyperthermia is seen mostly in pigs, but it has also been reported in dogs (especially Greyhounds), cats, and horses. This syndrome is characterized by abnormally high body temperature and muscle contraction that can potentially lead to death. A rapid and sudden increase in body temperature can be followed by muscle rigidity, a very rapid and irregular heartbeat, increased breathing rate, bluish tinge to skin and mucous membranes, unstable blood pressure, f
In both animals and people, fever may indicate infection, inflammation, an immune-mediated disease, or cancer. Determining the cause of a fever requires a history, physical examination, and sometimes laboratory or other diagnostic tests. Often, a fever resolves on its own or in response to antibiotic therapy. However, in a small percentage of animals, the fever continues or keeps coming back and the cause cannot be determined. This is called fever of unknown origin.
Owners commonly report muscular fatigue of dogs and horses. Muscular fatigue can be caused by numerous disorders of several body systems, which are discussed in other chapters. Fatigue is an issue for working dogs, racing greyhounds, and dogs that compete in agility and other high-intensity events.
Fatigue is a normal consequence of exercise that is continued at high intensity or for prolonged periods of time. It
Most disorders of magnesium metabolism are due to problems associated with absorption of the mineral from the digestive tract. The anatomical differences in the digestive tract between species are associated with the importance of disorders of magnesium occurring in a particular species. Disorders of magnesium metabolism are less common in dogs than in cattle and sheep. Too much magnesium in the blood (hypermagnesemia) is rare but has been r
Calcium is an essential component of the skeleton, and it has important functions in muscle contraction, blood clotting, enzyme activity, the nervous system, and hormone release, among others. Many different metabolic disorders affect calcium metabolism and can lead to abnormal levels of calcium in the blood. A high level of calcium is known as hypercalcemia, while a low one is called hypocalcemia
Metabolism refers to all processes in the body that break down and convert ingested substances to provide the energy and nutrients needed to sustain life. Foods, liquids, and drugs all generally undergo metabolic processes within the body. Many foods are complex materials that need to be broken down into simpler substances, which in turn become “building blocks” for the body to use as needed. For example, protein is broken down into amino acids, which are used
February 3, 2025
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